How would you rule?

[Steve M]

Mike,
You said
"First play, you've got my attention. I would agree if there was a lull in the play. If this was all continuous, I would have to take a lot into consideration. I may take into consideration how the runner on 2B came to be tagged. If it was obvious the runner was still involved in the play and got caught. ..."

Part of this depends on how we picture the original post. I pictured this with a bit of a lull. Like you said, if it is all continuous, then I've got something different.
In my picture, the defense noticed the missed 1B - havng played 1B, I'd have noticed when I played (that was part of my job). But, still in my picture, the defense knows that unless they get another out before they appeal the missed 1B, it's pointless. We ain't gonna wait all day on "pointless".