Assuming that #12 was just moseying out onto the field and didn't participate in the play, then in NCAA that would be treated as a dead ball foul. 5 yards from the succeeding spot.
So you'd penalize the block in the back 10 yards from the spot of the foul. Then march 5 yards the other way.
If #12 took part in the play, then it's a 15 yard penalty. So you'd probably penalize 10 yards for the block in the back, then 15 the other way.
[The NCAA rule actually allows the referee to enforce anything that he deems equitable, including awarding a score. But I think this is mostly for something like a guy coming out of the team area to tackle a ball carrier streaking down the sideline.]
Also, if the BIB occurred deep in R's territory, then R could accept offsetting fouls and replay the down.
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