It depends on what you mean by wiggle room. Where the OBS causes the runner to violate, then it makes sense to ignore the violation. The runner's violation would NOT have happened (we assume) without the defensive infraction.
On the other hand, if the runner's violation merely FOLLOWS (is NOT caused by) the OBS, then penalize both.
In the video, the coach's INT is independent and not caused by the OBS, so penalize it. The general principle remains: runners must run the bases correctly, even if hindered illegally by the defense.
[If I may say so, this discussion is getting a little metaphysical -- I'll throw something at whoever asks about Hume's Problem.
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