You Make The Call

[greymule]

With first and third, no outs, the run would count if it crossed the plate before the interference. The time of the interference, not the time of the pitch or anything else, is the determining factor. Of course, if the third out is a force, then no runs count, regardless of when any runs crossed.

A runner who crosses the plate is no longer a runner and can't be called out or sent back on interference that occurs afterward.

Interesting example of differences between ASA and OBR: R3 on 3B, R1 on 1B, one out. BR hits a double, moving R1 to 3B. R3 scored, but R1 missed 2B and BR missed 1B. In ASA, the defense must appeal 2B and then 1B for R3's run to be nullified. In OBR, the defense can appeal in any order; the run is nullified either way.