Initial receiver keys are the same in both 7- and 8- person mechanics.
Backs in the tackle box are ignored for purposes of determining initial keys.
Assuming nobody in motion:
F and S have the widest receiver on their side of the formation.
L and H have the second receiver (counting from the sideline towards the ball).
B has the 3rd receiver on the trips side. If there are two receivers on each side, B takes the 2nd receiver on L's side, and L shifts to the running back. If the 3rd receiver is a TE, B will initially key on the TE, but will switch to the 2nd receiver if the TE doesn't release down-field immediately at the snap (and H or L, depending on which side the TE's on, will switch from 2nd receiver to the TE).
If 4 receivers line up on one side, B takes 3rd and 4th receivers.
If a receiver is in motion, H and L are responsible for the motion man on their side of the ball, no matter where he is on the field relative to other receivers, and F/S/B switch their keys accordingly.
There's a couple wrinkles that I won't get into here... what I said above covers about 90% of situations.
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