Sitch:
R1 on 1st, R2 on 2nd. No outs. Count on the batter 0 and 2. Comes in strike three (PU calls "strike three, you're out"), and the catcher drops it. Batter-runner automatically runs to first (it is obvious that it is an automatic response and no nefarious intent was shown), and the catcher recovers the ball, throws to first. Overthrow, and the ball goes into right field. R1 scores, R2 ends up on 3rd base.
What is the call?
Do we say that the B-R is out (or rather R2 is out, because he is closest to home, and the B-R is out anyway) because of interference, or do we let the play stand, claiming that the players should know the rules and the situation?