Coach,
You might want to see if you can get information about Grinnell College in Iowa. They run an interesting substitute pattern where they're bringing in 5 players at a time about every 1 1/2 minutes. They've gotten some national attention (there was a short story on Fox sports last year. I've been to a game and it's kind of a fun game to watch (the game I saw ended up 168-155 in their favor). By the players admission, they play each possession like its the last of the game because they know they are getting a sub in just a few seconds. They've had pretty good success at their level, but I'm not sure it would work with better players. The difference in skill between their #1 guy and #12 guy is far less than in a division I school where your #1 guy is an All American and your #12 guy is a walk on. This doesn't solve your defensive match up problem, but I thought you might find it interesting.
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