missed 2nd base
 

with the bases loaded, the batter hits a ball to the outfield after a couple errors the batter makes it all the way home to score. the problem is the batter missed 2nd base and after appeal he is called out. how many runs would count in this situation? there were 2 outs on the play, but what if the were no outs or 1 out?

Regardless of the number of outs, 3 score. The out was not at first base and not a force out, so this is a timing play.

And had there been 2 outs, and a preceeding runner (let's say R2) called out on appeal for missing a base, no following runs (R1 and BR if R2 was called out) would score. But, in your case, since the batter-runner was the last runner, with no following runners, his out had no effect on the other three.